S100A8 promotes tumor progression by inducing phenotypic polarization of microglia through the TLR4/IL-10 signaling pathway in glioma

Background: S100A8 is a member of the S100 protein family and plays a pivotal role in regulating inflammation and tumor progression. This study aimed to comprehensively assess the expression patterns and functional roles of S100A8 in glioma progression. Methods: Glioma tissues were collected from 98...

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Bibliographic Details
Main Authors: Yuechao Yang, Huanhuan Cui, Deheng Li, Lei Chen, Yi Liu, Changshuai Zhou, Liangdong Li, Mingtao Feng, Xin Chen, Yiqun Cao, Yang Gao
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Journal of the National Cancer Center
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2667005424000784