Intergenerational reproductive toxicity of parental exposure to prothioconazole and its metabolite on offspring and epigenetic regulation associated with DNA methylation in zebrafish

Intergenerational reproductive toxicity of parental exposure to prothioconazole and its metabolite on offspring and epigenetic regulation associated with DNA methylation in zebrafish

Prothioconazole (PTC) is a widely used agricultural fungicide, and its parent and metabolite prothioconazole-desthio (dPTC) have been detected in diverse environmental media. This study was aimed at investigating the gender-dependent effects on adult zebrafish reproduction and intergenerational effe...

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Bibliographic Details
Main Authors: Sinuo Tian, Wei Sun, Xiaoxuan Sun, Yifan Yue, Ming Jia, Shiran Huang, Zhiqiang Zhou, Li Li, Jinling Diao, Sen Yan, Wentao Zhu
Format: Article
Language:English
Published: Elsevier 2023-03-01
Series:Environment International
Subjects:
DNA methylation
Offspring development
Prothioconazole
Reproduction
Zebrafish
Online Access:http://www.sciencedirect.com/science/article/pii/S0160412023001034

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http://www.sciencedirect.com/science/article/pii/S0160412023001034

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