The Underlying Mechanism of Modulation of Transient Receptor Potential Melastatin 3 by protons

The Underlying Mechanism of Modulation of Transient Receptor Potential Melastatin 3 by protons

Transient receptor potential melastatin 3 channel (TRPM3) is a calcium-permeable nonselective cation channel that plays an important role in modulating glucose homeostasis in the pancreatic beta cells. However, how TRPM3 is regulated under physiological and pathological conditions is poorly understo...

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Bibliographic Details
Main Authors: Md Zubayer Hossain Saad, Liuruimin Xiang, Yan-Shin Liao, Leah R. Reznikov, Jianyang Du
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Pharmacology
Subjects:
transient receptor potential channels
TRPM3
protons
Pregnenolone sulfate
site-directed mutagenesis
PH sensitivity
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.632711/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2021.632711/full

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