Chemokines Up-Regulated in Epithelial Cells Control Senescence-Associated T Cell Accumulation in Salivary Glands of Aged and Sjögren’s Syndrome Model Mice

Chemokines Up-Regulated in Epithelial Cells Control Senescence-Associated T Cell Accumulation in Salivary Glands of Aged and Sjögren’s Syndrome Model Mice

Immunosenescence is characterized by age-associated changes in immunological functions. Although age- and autoimmune-related sialadenitis cause dry mouth (xerostomia), the roles of immunosenescence and cellular senescence in the pathogenesis of sialadenitis remain unknown. We demonstrated that acqui...

Full description

Bibliographic Details
Main Authors: Mie Kurosawa, Yosuke Shikama, Masae Furukawa, Rieko Arakaki, Naozumi Ishimaru, Kenji Matsushita
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:International Journal of Molecular Sciences
Subjects:
sialadenitis
xerostomia
cellular senescence
immunosenescence
chemokines
Online Access:https://www.mdpi.com/1422-0067/22/5/2302

Internet

https://www.mdpi.com/1422-0067/22/5/2302

Similar Items