Multiple CAR-T cell therapy for acute B-cell lymphoblastic leukemia after hematopoietic stem cell transplantation: A case report

B-cell acute lymphoblastic leukemia (B-ALL) is the most common childhood malignancy. The cure rate has reached 90% after conventional chemotherapy and hematopoietic stem cell transplantation (HSCT), but the prognosis of patients with relapsed and refractory (R/R) leukemia is still poor after convent...

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Bibliographic Details
Main Authors: Lei Deng, Yu Xiaolin, Qian Wu, Xiaochen Song, Wenjun Li, Yixi Hou, Yue Liu, Jing Wang, Jun Tian, Xiaona Zuo, Fang Zhou
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.1039929/full