Macrophage extracellular vesicle-packaged miR-23a-3p impairs maintenance and angiogenic capacity of human endothelial progenitor cells in neonatal hyperoxia-induced lung injury

Macrophage extracellular vesicle-packaged miR-23a-3p impairs maintenance and angiogenic capacity of human endothelial progenitor cells in neonatal hyperoxia-induced lung injury

Abstract Background Premature infants requiring mechanical ventilation and supplemental oxygen for respiratory support are at increased risk for bronchopulmonary dysplasia (BPD), wherein inflammation have been proposed as a driver of hyperoxia-induced injuries, including persistent loss of endotheli...

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Bibliographic Details
Main Authors: Xuan Wang, Fang Yao, Lingling Yang, Dongshan Han, Yali Zeng, Zilu Huang, Chuanzhong Yang, Bingchun Lin, Xueyu Chen
Format: Article
Language:English
Published: BMC 2024-09-01
Series:Stem Cell Research & Therapy
Subjects:
Bronchopulmonary dysplasia
Endothelial progenitor cells
Inflammation
Extracellular vesicles
Cord blood
Intercellular communication
Online Access:https://doi.org/10.1186/s13287-024-03920-z

Internet

https://doi.org/10.1186/s13287-024-03920-z

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