Necdin, a p53-target gene, is an inhibitor of p53-mediated growth arrest.

In vitro, cellular immortalization and transformation define a model for multistep carcinogenesis and current ongoing challenges include the identification of specific molecular events associated with steps along this oncogenic pathway. Here, using NIH3T3 cells, we identified transcriptionally relat...

Full description

Bibliographic Details
Main Authors: Julie Lafontaine, Francis Rodier, Véronique Ouellet, Anne-Marie Mes-Masson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3280226?pdf=render