Structural diversity of tick-borne encephalitis virus particles in the inactivated vaccine based on strain Sofjin

Structural diversity of tick-borne encephalitis virus particles in the inactivated vaccine based on strain Sofjin

ABSTRACTThe main approach to preventing tick-borne encephalitis (TBE) is vaccination. Formaldehyde-inactivated TBE vaccines have a proven record of safety and efficiency but have never been characterized structurally with atomic resolution. We report a cryoelectron microscopy (cryo-EM) structure of...

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Bibliographic Details
Main Authors: Andrey Moiseenko, Yichen Zhang, Mikhail F. Vorovitch, Alla L. Ivanova, Zheng Liu, Dmitry I. Osolodkin, Alexey M. Egorov, Aydar A. Ishmukhametov, Olga S. Sokolova
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:Emerging Microbes and Infections
Subjects:
Tick-borne encephalitis virus
inactivated vaccines
cryoelectron microscopy
image analysis
variability analysis
asymmetry
Online Access:https://www.tandfonline.com/doi/10.1080/22221751.2023.2290833

Internet

https://www.tandfonline.com/doi/10.1080/22221751.2023.2290833

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