Controlled Release of Bone Morphogenetic Protein-2 Augments the Coupling of Angiogenesis and Osteogenesis for Accelerating Mandibular Defect Repair

Reconstruction of a mandibular defect is challenging, with high expectations for both functional and esthetic results. Bone morphogenetic protein-2 (BMP-2) is an essential growth factor in osteogenesis, but the efficacy of the BMP-2-based strategy on the bone regeneration of mandibular defects has n...

Full description

Bibliographic Details
Main Authors: Hao Yao, Jiaxin Guo, Wangyong Zhu, Yuxiong Su, Wenxue Tong, Lizhen Zheng, Liang Chang, Xinluan Wang, Yuxiao Lai, Ling Qin, Jiankun Xu
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Pharmaceutics
Subjects:
Online Access:https://www.mdpi.com/1999-4923/14/11/2397