Genetic Variants in CHIA and CHI3L1 Are Associated with the IgE Response to the Ascaris Resistance Marker ABA-1 and the Birch Pollen Allergen Bet v 1.

Genetic Variants in CHIA and CHI3L1 Are Associated with the IgE Response to the Ascaris Resistance Marker ABA-1 and the Birch Pollen Allergen Bet v 1.

Helminth infections and allergic diseases are associated with IgE hyperresponsiveness but the genetics of this phenotype remain to be defined. Susceptibility to Ascaris lumbricoides infection and antibody levels to this helminth are associated with polymorphisms in locus 13q33-34. We aimed to explor...

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Bibliographic Details
Main Authors: Nathalie Acevedo, Adriana Bornacelly, Dilia Mercado, Per Unneberg, Irene Mittermann, Rudolf Valenta, Malcolm Kennedy, Annika Scheynius, Luis Caraballo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5157985?pdf=render

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http://europepmc.org/articles/PMC5157985?pdf=render

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