Bone marrow mesenchymal stem cell-derived exosomal microRNA-381-3p alleviates vascular calcification in chronic kidney disease by targeting NFAT5

Abstract Vascular calcification (VC) is a significant complication of chronic kidney disease (CKD) and cellular apoptosis is one of the intricate mechanisms of VC. Bone marrow mesenchymal stem cell-derived exosome (BMSC-Exo) alleviates VC, but the mechanism remains unclear. We investigated the mecha...

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Bibliographic Details
Main Authors: Yingjie Liu, Yan Guo, Shumin Bao, Hongdong Huang, Wenhu Liu, Weikang Guo
Format: Article
Language:English
Published: Nature Publishing Group 2022-03-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-022-04703-1