Constrained hidden Markov models reveal further Hsp90 protein states

Constrained hidden Markov models reveal further Hsp90 protein states

Time series of conformational dynamics in proteins are usually evaluated with hidden Markov models (HMMs). This approach works well if the number of states and their connectivity is known. However, for the multi-domain protein Hsp90, a standard HMM analysis with optimization of the BIC (Bayesian inf...

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Bibliographic Details
Main Authors: Riccardo Tancredi, Antonio Feltrin, Giosuè Sardo Infirri, Simone Toso, Leonie Vollmar, Thorsten Hugel, Marco Baiesi
Format: Article
Language:English
Published: IOP Publishing 2024-01-01
Series:New Journal of Physics
Subjects:
hidden Markov models
protein dynamics
FRET experiments
Online Access:https://doi.org/10.1088/1367-2630/ad5def

Internet

https://doi.org/10.1088/1367-2630/ad5def

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