PARP7 and Mono-ADP-Ribosylation Negatively Regulate Estrogen Receptor α Signaling in Human Breast Cancer Cells

PARP7 and Mono-ADP-Ribosylation Negatively Regulate Estrogen Receptor α Signaling in Human Breast Cancer Cells

ADP-ribosylation is a post-translational protein modification catalyzed by a family of proteins known as poly-ADP-ribose polymerases. PARP7 (TIPARP; ARTD14) is a mono-ADP-ribosyltransferase involved in several cellular processes, including responses to hypoxia, innate immunity and regulation of nucl...

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Bibliographic Details
Main Authors: Marit Rasmussen, Susanna Tan, Venkata S. Somisetty, David Hutin, Ninni Elise Olafsen, Anders Moen, Jan H. Anonsen, Denis M. Grant, Jason Matthews
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Cells
Subjects:
PARP7
ARTD14
TIPARP
mono-ADP-ribosylation
estrogen receptor α
poly ADP-ribose polymerase
Online Access:https://www.mdpi.com/2073-4409/10/3/623

Internet

https://www.mdpi.com/2073-4409/10/3/623

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