Matteucinol combined with temozolomide inhibits glioblastoma proliferation, invasion, and progression: an in vitro, in silico, and in vivo study

Matteucinol combined with temozolomide inhibits glioblastoma proliferation, invasion, and progression: an in vitro, in silico, and in vivo study

Glioblastoma is the most prevalent and malignant brain tumor identified in adults. Surgical resection followed by radiotherapy and chemotherapy, mainly with temozolomide (TMZ), is the chosen treatment for this type of tumor. However, the average survival of patients is around 15 months. Novel approa...

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Bibliographic Details
Main Authors: J.B. Netto, E.S.A. Melo, A.G.S. Oliveira, L.R. Sousa, L.R. Santiago, D.M. Santos, R.C.R. Chagas, A.S. Gonçalves, R.G. Thomé, H.B. Santos, R.M. Reis, R.I.M.A. Ribeiro
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2022-08-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
Brain cancer
Antitumor
Natural products
Apoptosis
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2022000100656&lng=en&tlng=en

Internet

http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2022000100656&lng=en&tlng=en

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