H3K27 demethylase, JMJD3, regulates fragmentation of spermatogonial cysts.

The spermatogonial stem cell (SSC) compartment is maintained by self-renewal of stem cells as well as fragmentation of differentiating spermatogonia through abscission of intercellular bridges in a random and stochastic manner. The molecular mechanisms that regulate this reversible developmental lin...

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Bibliographic Details
Main Authors: Naoki Iwamori, Tokuko Iwamori, Martin M Matzuk
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3744460?pdf=render