Differential Neutralization of Unfractionated Heparin and Enoxaparin by Andexanet Alfa

Introduction Andexanet alfa (andexanet) is an approved antidote used to reverse the bleeding effects of Direct Oral Anticoagulant (Direct-Xa agents) agents because it reverses anti-Xa activity. Unfractionated heparin (UFH) and low molecular weight heparins (LMWHs) exhibit anti-Xa activity. The purpo...

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Bibliographic Details
Main Authors: Joseph Lewis BA, Omer Iqbal MD, Walter Jeske PhD, Debra Hoppensteadt PhD, Fakiha Siddiqui BDS, Jawed Fareed PhD
Format: Article
Language:English
Published: SAGE Publishing 2022-05-01
Series:Clinical and Applied Thrombosis/Hemostasis
Online Access:https://doi.org/10.1177/10760296221099934