N-Glycosylation as a Modulator of Protein Conformation and Assembly in Disease

N-Glycosylation as a Modulator of Protein Conformation and Assembly in Disease

Glycosylation, a prevalent post-translational modification, plays a pivotal role in regulating intricate cellular processes by covalently attaching glycans to macromolecules. Dysregulated glycosylation is linked to a spectrum of diseases, encompassing cancer, neurodegenerative disorders, congenital...

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Bibliographic Details
Main Authors: Chiranjeevi Pasala, Sahil Sharma, Tanaya Roychowdhury, Elisabetta Moroni, Giorgio Colombo, Gabriela Chiosis
Format: Article
Language:English
Published: MDPI AG 2024-02-01
Series:Biomolecules
Subjects:
N-glycosylation
disease
conformational mutant
aberrant protein assembly
energy landscape
SARS-CoV-2 spike protein
Online Access:https://www.mdpi.com/2218-273X/14/3/282

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https://www.mdpi.com/2218-273X/14/3/282

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