Self-assembly of pericentriolar material in interphase cells lacking centrioles

Self-assembly of pericentriolar material in interphase cells lacking centrioles

The major microtubule-organizing center (MTOC) in animal cells, the centrosome, comprises a pair of centrioles surrounded by pericentriolar material (PCM), which nucleates and anchors microtubules. Centrosome assembly depends on PCM binding to centrioles, PCM self-association and dynein-mediated PCM...

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Bibliographic Details
Main Authors: Fangrui Chen, Jingchao Wu, Malina K Iwanski, Daphne Jurriens, Arianna Sandron, Milena Pasolli, Gianmarco Puma, Jannes Z Kromhout, Chao Yang, Wilco Nijenhuis, Lukas C Kapitein, Florian Berger, Anna Akhmanova
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2022-07-01
Series:eLife
Subjects:
centrosome
microtubule
microtubule-organizing center
pericentriolar material
pericentrin
dynein
Online Access:https://elifesciences.org/articles/77892

Internet

https://elifesciences.org/articles/77892

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