Conformational Selection and Induced Fit: The Behavior of Two Homologous Proteases

Conformational Selection and Induced Fit: The Behavior of Two Homologous Proteases

Abstract Protein‐ligand interactions are crucial for many cellular processes, with details of the binding mechanism being discussed as essential for biological functions. Interestingly, protein binding often involves conformational changes between two or more states, whereby different binding mechan...

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Bibliographic Details
Main Authors: Hannah Maus, Gerald Hinze, Stefan J. Hammerschmidt, Prof. Dr. Tanja Schirmeister, Prof. Dr. Thomas Basché
Format: Article
Language:English
Published: Wiley-VCH 2023-11-01
Series:ChemistryEurope
Subjects:
binding mechanism of competitive inhibitors
flaviviral proteases
molecular dynamics
protein folding
smFRET
Online Access:https://doi.org/10.1002/ceur.202300060

Internet

https://doi.org/10.1002/ceur.202300060

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