Chicken telomerase reverse transcriptase promotes the tumorigenicity of avian leukosis virus subgroup J by regulating the Wnt/β-catenin signaling pathway

Abstract This research aimed to analyze the regulatory effect of chicken telomerase reverse transcriptase (chTERT) on the Wnt/β-catenin signaling pathway and its effect on the tumorigenicity of avian leukosis virus subgroup J (ALV-J) through in vivo experiments. The chTERT eukaryotic expression plas...

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Bibliographic Details
Main Authors: Yong Xiang, Canxin Liang, Qingbo Li, Qinxi Chen, Yang Zhou, Xiaoxue Zheng, Di Zhou, Zepeng Wang, Guyao Wang, Weisheng Cao
Format: Article
Language:English
Published: BMC 2022-12-01
Series:Veterinary Research
Subjects:
Online Access:https://doi.org/10.1186/s13567-022-01120-2