Role of HSV-1 Capsid Vertex-Specific Component (CVSC) and Viral Terminal DNA in Capsid Docking at the Nuclear Pore

Penetration of the viral genome into a host cell nucleus is critical for initiation of viral replication for most DNA viruses and a few RNA viruses. For herpesviruses, viral DNA ejection into a nucleus occurs when the capsid docks at the nuclear pore complex (NPC) basket with the correct orientation...

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Bibliographic Details
Main Authors: José Ramon Villanueva-Valencia, Efthymios Tsimtsirakis, Alex Evilevitch
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Viruses
Subjects:
Online Access:https://www.mdpi.com/1999-4915/13/12/2515