Correlation of peripheral CD4+GranzB+CTLs with disease severity in patients with primary Sjögren’s syndrome

Correlation of peripheral CD4+GranzB+CTLs with disease severity in patients with primary Sjögren’s syndrome

Abstract Introduction Primary Sjögren’s syndrome (pSS) is a chronic systemic autoimmune disease which has focal lymphocytic infiltration including a majority of CD4+ T cells. This study was to investigate the correlation of peripheral granzyme B (GranzB)-expressing CD4+ T cells with disease severity...

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Bibliographic Details
Main Authors: Qi Wang, Nan Che, Chengyin Lu, Xiaoxuan Sun, Yanyan Wang, Qiang Wang, Wenfeng Tan, Lanlan Zhou, Xiaojun Zhang, Dong Xu, Lei Gu, Miaojia Zhang
Format: Article
Language:English
Published: BMC 2021-10-01
Series:Arthritis Research & Therapy
Subjects:
Primary Sjögren’s syndrome
CD4+ T cells
CD4+GranzB+cytotoxic T cells
ESSDAI
Extraglandular manifestations
Online Access:https://doi.org/10.1186/s13075-021-02632-6

Internet

https://doi.org/10.1186/s13075-021-02632-6

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