The distribution of the modified Rankin scale scores change according to eligibility criteria in acute ischemic stroke trials: A consideration for sample size calculations when using ordinal regression analysis

The distribution of the modified Rankin scale scores change according to eligibility criteria in acute ischemic stroke trials: A consideration for sample size calculations when using ordinal regression analysis

Background: Distribution shifts of the modified Rankin scale (mRs) is used as outcome measure in acute ischemic stroke (AIS) randomized controlled trials (RCT). Distribution across strata of mRs is relevant for sample size calculations and may be affected by eligibility criteria. Aim: We aimed to as...

Full description

Bibliographic Details
Main Authors: Verónica V. Olavarría, Alejandro Brunser, Norberto Cabral, Sheila Martins, Paula Muñoz-Venturelli, Gabriel Cavada, Pablo M. Lavados
Format: Article
Language:English
Published: Elsevier 2017-03-01
Series:Contemporary Clinical Trials Communications
Subjects:
Stroke
Sample size
Clinical trials
Ordinal logistic regression
Online Access:http://www.sciencedirect.com/science/article/pii/S2451865416300680

Internet

http://www.sciencedirect.com/science/article/pii/S2451865416300680

Similar Items