Impact of intestinal microbiota on metabolic toxicity and potential detoxification of amygdalin

Amygdalin (Amy) is metabolized into cyanide in vivo, which may lead to fatal poisoning after oral administration. The defense mechanisms against toxic cyanide have not yet been adequately studied. In this study, comparative toxicokinetics study of Amy was performed in normal and pseudo germ-free rat...

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Bibliographic Details
Main Authors: Qiuyu Wen, Shen Yu, Shanshan Wang, Yan Qin, Quan Xia, Sheng Wang, Guanjun Chen, Chenlin Shen, Shuai Song
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Microbiology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2022.1030516/full