Vaccination using mutated receptor binding domains of SARS-CoV-2: Evidence for partial immune escape but not serotype formation

Vaccination using mutated receptor binding domains of SARS-CoV-2: Evidence for partial immune escape but not serotype formation

IntroductionSARS-CoV-2 has developed a number of Variants of Concern (VOC) with increased infectivity and/or reduced recognition by neutralizing antibodies specific for the receptor binding domain (RBD) of the spike protein. Extended studies of other viruses have shown that strong and broad viral es...

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Bibliographic Details
Main Authors: Xinyue Chang, Xuelan Liu, Byron Martina, Andris Zeltins, Gilles Augusto, Monique Vogel, Mona O. Mohsen, Daniel E. Speiser, Martin F. Bachmann
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-02-01
Series:Frontiers in Immunology
Subjects:
SARS–CoV–2
variants
serotype
immune escape
antibody
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1114396/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1114396/full

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