Oxytocin Suppresses Inflammatory Responses Induced by Lipopolysaccharide through Inhibition of the eIF-2α–ATF4 Pathway in Mouse Microglia

Microglia maintain brain homeostasis and modulate neuroinflammation and are implicated in the pathogenesis of various neurological diseases such as Alzheimer’s disease. In this study, we found that in lipopolysaccharide (LPS)-stimulated microglia, the endoplasmic reticulum (ER) stress-related eIF-2α...

Full description

Bibliographic Details
Main Authors: Takayuki Inoue, Hajime Yamakage, Masashi Tanaka, Toru Kusakabe, Akira Shimatsu, Noriko Satoh-Asahara
Format: Article
Language:English
Published: MDPI AG 2019-05-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/8/6/527