Cholinergic signaling via the α7 nicotinic acetylcholine receptor regulates the migration of monocyte-derived macrophages during acute inflammation

Cholinergic signaling via the α7 nicotinic acetylcholine receptor regulates the migration of monocyte-derived macrophages during acute inflammation

Abstract Background The involvement of the autonomic nervous system in the regulation of inflammation is an emerging concept with significant potential for clinical applications. Recent studies demonstrate that stimulating the vagus nerve activates the cholinergic anti-inflammatory pathway that inhi...

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Bibliographic Details
Main Authors: Kasey R. Keever, Kui Cui, Jared L. Casteel, Sanjay Singh, Donald B. Hoover, David L. Williams, Valentin A. Pavlov, Valentin P. Yakubenko
Format: Article
Language:English
Published: BMC 2024-01-01
Series:Journal of Neuroinflammation
Subjects:
Cholinergic anti-inflammatory pathway
α7nAChR
Macrophage
Migration
Endotoxemia
Sepsis
Online Access:https://doi.org/10.1186/s12974-023-03001-7

Internet

https://doi.org/10.1186/s12974-023-03001-7

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