Multiplex Matrix Metalloproteinases Analysis in the Cerebrospinal Fluid Reveals Potential Specific Patterns in Multiple Sclerosis Patients

Background: Matrix metalloproteinases (MMPs) are pleiotropic enzymes involved in extracellular protein degradation and turnover. MMPs are implicated in the pathogenesis of many neurological diseases, including multiple sclerosis (MS).Objective: To search the level of MMPs in the cerebrospinal fluid...

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Main Authors: Massimiliano Castellazzi, Daniela Ligi, Elena Contaldi, Davide Quartana, Mattia Fonderico, Luca Borgatti, Tiziana Bellini, Alessandro Trentini, Enrico Granieri, Enrico Fainardi, Ferdinando Mannello, Maura Pugliatti
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-12-01
Series:Frontiers in Neurology
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Online Access:https://www.frontiersin.org/article/10.3389/fneur.2018.01080/full