The function and regulation of PD-L1 in immunotherapy

PD-L1, also known as B7-H1, is a type I transmembrane protein, which is expressed in different kinds of tumor cells. It is correlated with poor clinical outcome of patients with various types of tumors. PD-L1 can regulate tumor microenvironment or tumor related immune response through suppressing T...

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Bibliographic Details
Main Authors: Libin Guo, Yao Lin, Hang Fai Kwok
Format: Article
Language:English
Published: International Association of Physical Chemists (IAPC) 2017-09-01
Series:ADMET and DMPK
Online Access:http://pub.iapchem.org/ojs/index.php/admet/article/view/442