Differential Regulation of Two Arms of mTORC1 Pathway Fine-Tunes Global Protein Synthesis in Resting B Lymphocytes

Differential Regulation of Two Arms of mTORC1 Pathway Fine-Tunes Global Protein Synthesis in Resting B Lymphocytes

Protein synthesis is tightly regulated by both gene-specific and global mechanisms to match the metabolic and proliferative demands of the cell. While the regulation of global protein synthesis in response to mitogen or stress signals is relatively well understood in multiple experimental systems, h...

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Bibliographic Details
Main Authors: Gagan Dev, Amanpreet Singh Chawla, Suman Gupta, Vineeta Bal, Anna George, Satyajit Rath, G. Aneeshkumar Arimbasseri
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:International Journal of Molecular Sciences
Subjects:
protein synthesis
mTORC1
4EBP1
Ribo-Seq
B cell
T cell
Online Access:https://www.mdpi.com/1422-0067/23/24/16017

Internet

https://www.mdpi.com/1422-0067/23/24/16017

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