The Role of CDK4 in the Pathogenesis of Pancreatic Cancer

Pancreatic cancer (PC) continues to have the lowest overall survival and the lack of effective early diagnosis. Cyclin-dependent kinase 4 (CDK4) plays a fundamental role in the orderly progression of the cell cycle, binding to cyclin D to promote the progression through the G1/2 transition. The inhi...

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Bibliographic Details
Main Authors: Emily Jiggens, Maria Mortoglou, Guy H. Grant, Pinar Uysal-Onganer
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:Healthcare
Subjects:
Online Access:https://www.mdpi.com/2227-9032/9/11/1478