Transglutaminase Activity Is Conserved in Stratified Epithelia and Skin Appendages of Mammals and Birds

Transglutaminase Activity Is Conserved in Stratified Epithelia and Skin Appendages of Mammals and Birds

The cross-linking of structural proteins is critical for establishing the mechanical stability of the epithelial compartments of the skin and skin appendages. The introduction of isopeptide bonds between glutamine and lysine residues depends on catalysis by transglutaminases and represents the main...

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Bibliographic Details
Main Authors: Attila Placido Sachslehner, Marta Surbek, Bahar Golabi, Miriam Geiselhofer, Karin Jäger, Claudia Hess, Ulrike Kuchler, Reinhard Gruber, Leopold Eckhart
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:International Journal of Molecular Sciences
Subjects:
transglutaminase
cornification
keratinocytes
epidermis
filiform papillae
nail
Online Access:https://www.mdpi.com/1422-0067/24/3/2193

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https://www.mdpi.com/1422-0067/24/3/2193

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