Interferon-tau attenuates uptake of nanoparticles and secretion of interleukin-1β in macrophages.

BACKGROUND: Type I interferons (IFNs), including IFN-alpha (IFNA) and IFN-beta (IFNB), have anti-inflammatory properties and are used to treat patients with autoimmune and inflammatory disorders. However, little is known of the role of IFN-tau (IFNT), a type I IFN produced by ruminant animals for in...

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Main Authors: Kyoko Hara, Koumei Shirasuna, Fumitake Usui, Tadayoshi Karasawa, Yoshiko Mizushina, Hiroaki Kimura, Akira Kawashima, Akihide Ohkuchi, Shuichi Matsuyama, Koji Kimura, Masafumi Takahashi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4259327?pdf=render