Ribociclib-induced liver injury: a case report

Ribociclib-induced liver injury: a case report

BackgroundIdiosyncratic drug-induced liver injury (DILI) is a rare, unpredictable hepatic adverse event and the most common cause of acute liver failure in Europe and the US. Ribociclib is a potent Cyclin-dependent kinase 4 and 6 (CDK4/6)-inhibitor administered for advanced hormone-receptor (HR)-pos...

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Bibliographic Details
Main Authors: Sofia Schaeffer, Christian Lutz, Michael Dobbie, Luigi M. Terracciano, Matthias Matter, Jürg Vosbeck, Markus H. Heim, Christine Bernsmeier
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-12-01
Series:Frontiers in Oncology
Subjects:
CDK 4/6 inhibitor
ribociclib
hepatotoxicity
DILI
liver necrosis
Hormone-positive HER2-negative breast cancer
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2023.1256783/full

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https://www.frontiersin.org/articles/10.3389/fonc.2023.1256783/full

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