Synthetic production of prenylated naringenins in yeast using promiscuous microbial prenyltransferases

Synthetic production of prenylated naringenins in yeast using promiscuous microbial prenyltransferases

Reconstitution of prenylflavonoids using the flavonoid biosynthetic pathway and prenyltransferases (PTs) in microbes can be a promising attractive alternative to plant-based production or chemical synthesis. Here, we demonstrate that promiscuous microbial PTs can be a substitute for regiospecific bu...

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Bibliographic Details
Main Authors: Shota Isogai, Nobuyuki Okahashi, Ririka Asama, Tomomi Nakamura, Tomohisa Hasunuma, Fumio Matsuda, Jun Ishii, Akihiko Kondo
Format: Article
Language:English
Published: Elsevier 2021-06-01
Series:Metabolic Engineering Communications
Subjects:
Prenylnaringenin
Prenyltransferase
Naringenin
Prenylflavonoids
Yeast
Online Access:http://www.sciencedirect.com/science/article/pii/S2214030121000092

Internet

http://www.sciencedirect.com/science/article/pii/S2214030121000092

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