A tandem motif-based and structural approach can identify hidden functional phosphodiesterases

Cyclic nucleotide monophosphates (cNMPs) are increasingly recognized as essential signaling molecules governing many physiological and developmental processes in prokaryotes and eukaryotes. Degradation of cNMPs is as important as their generation because it offers the capability for transient and dy...

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Bibliographic Details
Main Authors: Mateusz Kwiatkowski, Aloysius Wong, Anna Kozakiewicz, Christoph Gehring, Krzysztof Jaworski
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:Computational and Structural Biotechnology Journal
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2001037021000404