Targeted haplotyping in pharmacogenomics using Oxford Nanopore Technologies’ adaptive sampling

Pharmacogenomics (PGx) studies the impact of interindividual genomic variation on drug response, allowing the opportunity to tailor the dosing regimen for each patient. Current targeted PGx testing platforms are mainly based on microarray, polymerase chain reaction, or short-read sequencing. Despite...

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Bibliographic Details
Main Authors: Koen Deserranno, Laurentijn Tilleman, Kaat Rubben, Dieter Deforce, Filip Van Nieuwerburgh
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-11-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2023.1286764/full