Resident Self-Tissue of Proinflammatory Cytokines Rather Than Their Systemic Levels Correlates with Development of Myelofibrosis in <i>Gata1</i><sup>low</sup> Mice

Resident Self-Tissue of Proinflammatory Cytokines Rather Than Their Systemic Levels Correlates with Development of Myelofibrosis in <i>Gata1</i><sup>low</sup> Mice

Serum levels of inflammatory cytokines are currently investigated as prognosis markers in myelofibrosis, the most severe Philadelphia-negative myeloproliferative neoplasm. We tested this hypothesis in the <i>Gata1</i><sup>low</sup> model of myelofibrosis. <i>Gata1</i...

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Bibliographic Details
Main Authors: Maria Zingariello, Paola Verachi, Francesca Gobbo, Fabrizio Martelli, Mario Falchi, Maria Mazzarini, Mauro Valeri, Giuseppe Sarli, Christian Marinaccio, Johanna Melo-Cardenas, John D. Crispino, Anna Rita Migliaccio
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Biomolecules
Subjects:
myelofibrosis
GATA1
proinflammatory cytokines
TGF-β1
interleukin 8
megakaryocytes
Online Access:https://www.mdpi.com/2218-273X/12/2/234

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https://www.mdpi.com/2218-273X/12/2/234

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