Interplay Between Mitochondrial Oxidative Disorders and Proteostasis in Alzheimer’s Disease

Interplay Between Mitochondrial Oxidative Disorders and Proteostasis in Alzheimer’s Disease

Although the basis of Alzheimer’s disease (AD) etiology remains unknown, oxidative stress (OS) has been recognized as a prodromal factor associated to its progression. OS refers to an imbalance between oxidant and antioxidant systems, which usually consist in an overproduction of reactive oxygen spe...

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Bibliographic Details
Main Authors: Emilio Llanos-González, Ángel Andres Henares-Chavarino, Cristina María Pedrero-Prieto, Sonia García-Carpintero, Javier Frontiñán-Rubio, Francisco Javier Sancho-Bielsa, Francisco Javier Alcain, Juan Ramón Peinado, Yoana Rabanal-Ruíz, Mario Durán-Prado
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-01-01
Series:Frontiers in Neuroscience
Subjects:
Alzheimer’s disease
autophagy
endoplasmic reticulum stress
oxidative stress
proteasomal degradation
unfolded protein response
Online Access:https://www.frontiersin.org/article/10.3389/fnins.2019.01444/full

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https://www.frontiersin.org/article/10.3389/fnins.2019.01444/full

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