Nanomechanical properties of α-synuclein amyloid fibrils: a comparative study by nanoindentation, harmonic force microscopy, and Peakforce QNM

<p>Abstract</p> <p>We report on the use of three different atomic force spectroscopy modalities to determine the nanomechanical properties of amyloid fibrils of the human &#945;-synuclein protein. &#945;-Synuclein forms fibrillar nanostructures of approximately 10 nm diamet...

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Bibliographic Details
Main Authors: Sweers Kim, van der Werf Kees, Bennink Martin, Subramaniam Vinod
Format: Article
Language:English
Published: SpringerOpen 2011-01-01
Series:Nanoscale Research Letters
Online Access:http://www.nanoscalereslett.com/content/6/1/270