Corilagin inhibits SARS-CoV-2 replication by targeting viral RNA-dependent RNA polymerase

Corilagin inhibits SARS-CoV-2 replication by targeting viral RNA-dependent RNA polymerase

Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has become one major threat to human population health. The RNA-dependent RNA polymerase (RdRp) presents an ideal target of antivirals, whereas nucleoside analogs inhibitor is hindered by the proofreading activity of coronavirus. Herein, w...

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Bibliografski detalji
Glavni autori: Quanjie Li, Dongrong Yi, Xiaobo Lei, Jianyuan Zhao, Yongxin Zhang, Xiangling Cui, Xia Xiao, Tao Jiao, Xiaojing Dong, Xuesen Zhao, Hui Zeng, Chen Liang, Lili Ren, Fei Guo, Xiaoyu Li, Jianwei Wang, Shan Cen
Format: Članak
Jezik:English
Izdano: Elsevier 2021-06-01
Serija:Acta Pharmaceutica Sinica B
Teme:
SARS-CoV-2
RdRp
Structure-based virtual screening
Viral replication
Non-nucleoside inhibitor
Drug combinations
Online pristup:http://www.sciencedirect.com/science/article/pii/S2211383521000496

Internet

http://www.sciencedirect.com/science/article/pii/S2211383521000496

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