Single-cell RNA-seq analysis reveals dual sensing of HIV-1 in blood Axl+ dendritic cells

Summary: Sensing of incoming viruses is a pivotal task of dendritic cells (DCs). Human primary blood DCs encompass various subsets that are diverse in their susceptibility and response to HIV-1. The recent identification of the blood Axl+DC subset, endowed with unique capacities to bind, replicate,...

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Bibliographic Details
Main Authors: Flavien Brouiller, Francesca Nadalin, Pierre-Emmanuel Bonté, Ouardia Ait-Mohamed, Constance Delaugerre, Jean-Daniel Lelièvre, Florent Ginhoux, Nicolas Ruffin, Philippe Benaroch
Format: Article
Language:English
Published: Elsevier 2023-02-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004223000962