Prior exposure to B. pertussis shapes the mucosal antibody response to acellular pertussis booster vaccination

Prior exposure to B. pertussis shapes the mucosal antibody response to acellular pertussis booster vaccination

Bordetella pertussis (Bp), the causative agent of pertussis, continues to circulate and it’s not well understood how (sub)clinical infections shape immune memory to Bp and vaccination. Here, using a mutant Bp strain lacking antigens of the acellular pertussis vaccine, the authors show how prior expo...

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Bibliographic Details
Main Authors: Evi van Schuppen, Janeri Fröberg, Prashanna Balaji Venkatasubramanian, Pauline Versteegen, Hans de Graaf, Jana Holubová, Joshua Gillard, Pieter G. M. van Gageldonk, Irma Joosten, Ronald de Groot, Peter Šebo, Guy A. M. Berbers, Robert C. Read, Martijn A. Huynen, Marien I. de Jonge, Dimitri A. Diavatopoulos
Format: Article
Language:English
Published: Nature Portfolio 2022-12-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-022-35165-w

Internet

https://doi.org/10.1038/s41467-022-35165-w

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