Downregulation of a Dorsal Root Ganglion‐Specifically Enriched Long Noncoding RNA is Required for Neuropathic Pain by Negatively Regulating RALY‐Triggered Ehmt2 Expression

Downregulation of a Dorsal Root Ganglion‐Specifically Enriched Long Noncoding RNA is Required for Neuropathic Pain by Negatively Regulating RALY‐Triggered Ehmt2 Expression

Abstract Nerve injury‐induced maladaptive changes of gene expression in dorsal root ganglion (DRG) neurons contribute to neuropathic pain. Long non‐coding RNAs (lncRNAs) are emerging as key regulators of gene expression. Here, a conserved lncRNA is reported, named DRG‐specifically enriched lncRNA (D...

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Bibliographic Details
Main Authors: Zhiqiang Pan, Shibin Du, Kun Wang, Xinying Guo, Qingxiang Mao, Xiaozhou Feng, Lina Huang, Shaogen Wu, Bailing Hou, Yun‐Juan Chang, Tong Liu, Tong Chen, Hong Li, Thomas Bachmann, Alex Bekker, Huijuan Hu, Yuan‐Xiang Tao
Format: Article
Language:English
Published: Wiley 2021-07-01
Series:Advanced Science
Subjects:
Dorsal root ganglion
DRG‐specifically enriched long noncoding RNA
Ehmt2
G9a
Neuropathic pain
RALY
Online Access:https://doi.org/10.1002/advs.202004515

Internet

https://doi.org/10.1002/advs.202004515

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