LncRNA–mRNA expression profile and functional network of vascular dysfunction in septic rats

Abstract Background We used microarrays to analyse the changes in long non-coding RNAs (lncRNAs) and mRNAs in aorta tissue in model rats with lipopolysaccharide-induced sepsis and determined the lncRNA–mRNA and lncRNA–miRNA–mRNA functional networks. Methods Wistar rats were intraperitoneally injecte...

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Bibliographic Details
Main Authors: Ye-Chen Han, Zhu-Jun Shen, Yi-Ning Wang, Ruo-Lan Xiang, Hong-Zhi Xie
Format: Article
Language:English
Published: BMC 2023-01-01
Series:European Journal of Medical Research
Subjects:
Online Access:https://doi.org/10.1186/s40001-022-00961-z