Insulin replacement prevents the acquisition but not the expression of morphine-induced conditioned place preference in streptozotocin-induced diabetic rats

Abstract Insulin receptors have distributed in all brain regions, including the nucleus Accumbens (NAc), and where is implicated in the reward properties of drugs. It is well known that insulin signaling can regulate dopamine release. Therefore, in the present study, we tried to examine the effect o...

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Bibliographic Details
Main Authors: Rezvan Hassanpour, Atieh Chizari, Amir-Hossein Bayat, Ronak Azizbeigi, Maedeh Mahmoudi, Zahra Mousavi, Abbas Haghparast
Format: Article
Language:English
Published: Universidade de São Paulo 2022-12-01
Series:Brazilian Journal of Pharmaceutical Sciences
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502022000100797&tlng=en