Oral minimal model-based estimates of insulin sensitivity in obese youth depend on oral glucose tolerance test protocol duration

Oral minimal model-based estimates of insulin sensitivity in obese youth depend on oral glucose tolerance test protocol duration

Introduction: The Oral Minimal Model (OMM), a differential-equations based mathematical model of glucose-insulin dynamics, utilizes data from a frequently sampled oral glucose tolerance test (OGTT) to quantify insulin sensitivity (SI). OMM-based estimates of SI can detect differences in insulin resi...

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Bibliographic Details
Main Authors: Kai Bartlette, Anne-Marie Carreau, Danielle Xie, Yesenia Garcia-Reyes, Haseeb Rahat, Laura Pyle, Kristen J. Nadeau, Melanie Cree-Green, Cecilia Diniz Behn
Format: Article
Language:English
Published: Elsevier 2021-03-01
Series:Metabolism Open
Subjects:
Insulin sensitivity
Mathematical model
Protocol dependence
Oral glucose tolerance test
Pediatrics
Online Access:http://www.sciencedirect.com/science/article/pii/S2589936821000025

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http://www.sciencedirect.com/science/article/pii/S2589936821000025

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