Lipid core nanoparticles resembling low-density lipoprotein and regression of atherosclerotic lesions: effects of particle size

Lipid core nanoparticles resembling low-density lipoprotein and regression of atherosclerotic lesions: effects of particle size

Particles are usually polydispersed and size is an important feature for lipid-based drug delivery systems in order to optimize cell-particle interactions as to pharmacologic action and toxicity. Lipid nanoparticles (LDE) with composition similar to that of low-density lipoprotein carrying paclitaxe...

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Bibliographic Details
Main Authors: S.C.M.P. Freitas, E.R. Tavares, B.M.O. Silva, B.C. Meneghini, R. Kalil-Filho, R.C. Maranhão
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2018-03-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
Solid lipid nanoparticles
Drug targeting
Paclitaxel
Atherosclerosis
Particle size
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2018000300612&lng=en&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2018000300612&lng=en&tlng=en

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