Clinically relevant plasma proteome for adiposity depots: evidence from systematic mendelian randomization and colocalization analyses

Abstract Background The accumulation of visceral and ectopic fat comprise a major cause of cardiometabolic diseases. However, novel drug targets for reducing unnecessary visceral and ectopic fat are still limited. Our study aims to provide a comprehensive investigation of the causal effects of the p...

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Bibliographic Details
Main Authors: Min Cao, Bin Cui
Format: Article
Language:English
Published: BMC 2024-04-01
Series:Cardiovascular Diabetology
Subjects:
Online Access:https://doi.org/10.1186/s12933-024-02222-1