Sodium aescinate inhibits microglia activation through NF-κB pathway and exerts neuroprotective effect

Sodium aescinate inhibits microglia activation through NF-κB pathway and exerts neuroprotective effect

Background: Microglia are resident immune cells of the central nervous system that sense environmental changes and maintain central nervous system homeostasis. Dysfunctional microglia produce toxic mediators that lead to neuronal death. Recent studies suggest that Sodium Aescinate has a neuroprotect...

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Bibliographic Details
Main Authors: Fei Xu, Yiguo Jiang, Xiaoyu Wang, Li Shen, Yan Yan, Dongkai Guo, Cheng Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Pharmacology
Subjects:
sodium aescinate
microglia
NF-κB pathway
neuroinflammation
molecular docking
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2023.1086429/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2023.1086429/full

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